Blood Transcriptional Profiling Reveals Immunological Signatures of Distinct States of Infection of Humans with Leishmania infantum.

Visceral leishmaniasis (VL) can be lethal if untreated; however, the majority of human infections with the etiological agents are asymptomatic. Using Illumina Bead Chip microarray technology, we investigated the patterns of gene expression in blood of active VL patients, asymptomatic infected indivi...

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Bibliographic Details
Main Authors: Luiz Gustavo Gardinassi, Gustavo Rocha Garcia, Carlos Henrique Nery Costa, Vladimir Costa Silva, Isabel Kinney Ferreira de Miranda Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5102635?pdf=render