Dynamic Observation of Autophagy and Transcriptome Profiles in a Mouse Model of Bleomycin-Induced Pulmonary Fibrosis

Dynamic Observation of Autophagy and Transcriptome Profiles in a Mouse Model of Bleomycin-Induced Pulmonary Fibrosis

Pulmonary fibrosis is a group of progressive, fibrotic, and fatal lung diseases, and the role of autophagy in pulmonary fibrosis is controversial. In the current research, we dynamically observed a bleomycin-induced pulmonary fibrosis mouse model after 3, 7, 14, 21, and 28 days and investigated the...

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Bibliographic Details
Main Authors: Yani Wang, Siqi Hu, Lisha Shen, Song Liu, Linyan Wan, Shuhui Yang, Mengjie Hou, Xinlun Tian, Hongbing Zhang, Kai-Feng Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
idiopathic pulmonary fibrosis
autophagy
RNA-Seq
STEM
bleomycin mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.664913/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.664913/full

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