Elevated Cholesterol in the Coxiella burnetii Intracellular Niche Is Bacteriolytic
Coxiella burnetii is an intracellular bacterial pathogen and a significant cause of culture-negative endocarditis in the United States. Upon infection, the nascent Coxiella phagosome fuses with the host endocytic pathway to form a large lysosome-like vacuole called the parasitophorous vacuole (PV)....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2017-02-01
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| Series: | mBio |
| Online Access: | http://mbio.asm.org/cgi/content/full/8/1/e02313-16 |