Peptides derived from cadherin juxtamembrane region inhibit platelet function

The juxtamembrane domains (JMD) of transmembrane proteins are rich in critical peptide sequences that participate in dynamic cell signalling events. Synthetic JMD peptides derived from cadherin cell adhesion proteins have previously been shown to modulate platelet function. In this study, we aimed t...

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Bibliographic Details
Main Authors: Kalyan Golla, Ilias Stavropoulos, Denis C. Shields, Niamh Moran
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.172347