Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells

Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells

Abstract Background We have previously demonstrated the anticancer effect of anthocyanins. In this study, we explored the biological activities of delphinidin, the most common of the anthocyanidin monomers, that were related to autophagy in HER-2 positive breast cancer MDA-MB-453 and BT474 cells. Me...

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Bibliographic Details
Main Authors: Jingyao Chen, Yanfeng Zhu, Weiwei Zhang, Xiaoli Peng, Jie Zhou, Fei Li, Bin Han, Xin Liu, Yu Ou, Xiaoping Yu
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Cancer
Subjects:
Delphinidin
Apoptosis
Autophagy
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-4231-y

Internet

http://link.springer.com/article/10.1186/s12885-018-4231-y

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