Autophagy and the Oncogene-induced Senescence

The oncogene-induced senescence is emerging as a potent tumor suppressor mechanism and as a possible therapeutic target. Macroautophagy is intimately linked to the senescence condition setup, although its role has not been elucidated yet. Here we discuss up-to-date concepts of senescence-related mac...

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Bibliographic Details
Main Authors: Daniel eGrasso, Maria Ines Vaccaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00157/full