Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection

Functional Genomics and Immunologic Tools: The Impact of Viral and Host Genetic Variations on the Outcome of Zika Virus Infection

Zika virus (ZIKV) causes no-to-mild symptoms or severe neurological disorders. To investigate the importance of viral and host genetic variations in determining ZIKV infection outcomes, we created three full-length infectious cDNA clones as bacterial artificial chromosomes for each of three spatiote...

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Bibliographic Details
Main Authors: Sang-Im Yun, Byung-Hak Song, Jordan C. Frank, Justin G. Julander, Aaron L. Olsen, Irina A. Polejaeva, Christopher J. Davies, Kenneth L. White, Young-Min Lee
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Viruses
Subjects:
Zika virus
flavivirus
infectious cDNA
replication
gene expression
neuropathogenesis
viral genetic variation
host genetic variation
Online Access:http://www.mdpi.com/1999-4915/10/8/422

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http://www.mdpi.com/1999-4915/10/8/422

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