Single and Binge Methamphetamine Administrations Have Different Effects on the Levels of Dopamine D2 Autoreceptor and Dopamine Transporter in Rat Striatum

Single and Binge Methamphetamine Administrations Have Different Effects on the Levels of Dopamine D2 Autoreceptor and Dopamine Transporter in Rat Striatum

Methamphetamine (METH) is a central nervous system psychostimulant with a high potential for abuse. At high doses, METH causes a selective degeneration of dopaminergic terminals in the striatum. Dopamine D2 receptor antagonists and dopamine transporter (DAT) inhibitors protect against neurotoxicity...

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Bibliographic Details
Main Authors: Heli Chauhan, Bryan A. Killinger, Cheryl V. Miller, Anna Moszczynska
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:International Journal of Molecular Sciences
Subjects:
dopamine D2 receptor
dopamine transporter
methamphetamine
striatum
in vivo
Online Access:http://www.mdpi.com/1422-0067/15/4/5884

Internet

http://www.mdpi.com/1422-0067/15/4/5884

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