Zoledrinic Acid Induces Steoblastic Differentiation of Mesenchymal Stem Cells without Change in Hypomethylation Status of OSTERIX Promoter

Zoledrinic Acid Induces Steoblastic Differentiation of Mesenchymal Stem Cells without Change in Hypomethylation Status of OSTERIX Promoter

Objective: Mechanism of zoledronic acid on osteoblastic differentiation of mesenchymal stem cells (MSCs) has not fully understood. With the knowledge of some drugs mechanism that alter methylation pattern of some genes, the present research sets out to evaluate osterix (OSX) promoter methylation pat...

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Bibliographic Details
Main Authors: Maryam Mahmodinia Maymand, Saeid Kaviani, Masoud Soleimani, Yousef Mortazavi, Mehrdad Noruzinia, Majid Farshdousti Hagh
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2012-01-01
Series:Cell Journal
Subjects:
Zoledronic Acid
Osteoblastic Differentiation
Mesenchymal Stem Cells
Methylation
OSX
Online Access:http://celljournal.org/library/upload/article/af_3823223467265423226383524632563746635333farshdousti.pdf

Internet

http://celljournal.org/library/upload/article/af_3823223467265423226383524632563746635333farshdousti.pdf

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