Border Patrol Gone Awry: Lung NKT Cell Activation by Francisella tularensis Exacerbates Tularemia-Like Disease.

The respiratory mucosa is a major site for pathogen invasion and, hence, a site requiring constant immune surveillance. The type I, semi-invariant natural killer T (NKT) cells are enriched within the lung vasculature. Despite optimal positioning, the role of NKT cells in respiratory infectious disea...

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Bibliographic Details
Main Authors: Timothy M Hill, Pavlo Gilchuk, Basak B Cicek, Maria A Osina, Kelli L Boyd, Douglas M Durrant, Dennis W Metzger, Kamal M Khanna, Sebastian Joyce
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4465904?pdf=render