Haemophilus parasuis α-2,3-sialyltransferase-mediated lipooligosaccharide sialylation contributes to bacterial pathogenicity

Haemophilus parasuis α-2,3-sialyltransferase-mediated lipooligosaccharide sialylation contributes to bacterial pathogenicity

Bacterial lipooligosaccharide (LOS) is an important virulence-associated factor, and its sialylation largely confers its ability to mediate cell adhesion, invasion, inflammation, and immune evasion. Here, we investigated the function of the Haemophilus parasuis α-2,3-sialyltransferase gene, lsgB, wh...

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Bibliographic Details
Main Authors: Huan Wang, Lu Liu, Qi Cao, Weiting Mao, Yage Zhang, Xinyi Qu, Xuwang Cai, Yujin Lv, Huanchun Chen, Xiaojuan Xu, Xiangru Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
α-2
3-sialyltransferase
lsgB
LOS sialylation
adhesion and invasion
serum resistance
pathogenicity
Online Access:http://dx.doi.org/10.1080/21505594.2018.1502606

Internet

http://dx.doi.org/10.1080/21505594.2018.1502606

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