The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs

Abstract Variability in disease development due to differences in strains and breeders constitutes a substantial challenge in preclinical research. However, the impact of the breeder on non-alcoholic steatohepatitis (NASH) is not yet fully elucidated. This retrospective study investigates NASH devel...

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Bibliographic Details
Main Authors: D. H. Ipsen, R. H. Agerskov, J. H. Klaebel, J. Lykkesfeldt, Pernille Tveden-Nyborg
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82643-0