Preparation of a novel monoclonal antibody against caprine interleukin-17A and its applications in immunofluorescence and immunohistochemistry assays

Abstract Background Interleukin-17 (IL-17), the characteristic cytokine secreted by T helper 17 lymphocytes (Th17 cells), plays a pivotal role in host defense and many inflammatory or autoimmune diseases. The aim of this study was to obtain purified protein caprine IL-17A (cIL-17A) as an antigen for...

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Bibliographic Details
Main Authors: Yang Gao, Feng Feng Sang, De Lan Meng, Yi Wang, Wen Tao Ma, De Kun Chen
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Biotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12896-019-0543-5