Decoupling of Nrf2 Expression Promotes Mesenchymal State Maintenance in Non-Small Cell Lung Cancer

Decoupling of Nrf2 Expression Promotes Mesenchymal State Maintenance in Non-Small Cell Lung Cancer

Epithelial mesenchymal transition is a common mechanism leading to metastatic dissemination and cancer progression. In an effort to better understand this process we found an intersection of Nrf2/NLE2F2 (Nrf2), epithelial mesenchymal transition (EMT), and metabolic alterations using multiple in vitr...

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Bibliographic Details
Main Authors: John A. Haley, Christian F. Ruiz, Emily D. Montal, Daifeng Wang, John D. Haley, Geoffrey D. Girnun
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
nrf2
epithelial mesenchymal transition
glycolysis
tca cycle
lipogenesis
redox signaling
Online Access:https://www.mdpi.com/2072-6694/11/10/1488

Internet

https://www.mdpi.com/2072-6694/11/10/1488

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