Altered Gene Expression in an Embolic Stroke Model After Thrombolysis With Tissue Plasminogen Activator and Stachybotrys microspora Triprenyl Phenol-7

Abstract.: The present study compares gene expression and infarct area in a mouse model of embolic stroke after thrombolysis with t-PA and SMTP-7. Embolic occlusion was induced by transfer of acetic acid–induced embolus into the brain. t-PA or SMTP-7 was administered 3 h after embolization. Changes...

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Bibliographic Details
Main Authors: Terumasa Hashimoto, Keita Shibata, Hisayuki Ohata, Keiji Hasumi, Kazuo Honda
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301574