LncRNA SNHG15 contributes to doxorubicin resistance of osteosarcoma cells through targeting the miR-381-3p/GFRA1 axis

LncRNA SNHG15 contributes to doxorubicin resistance of osteosarcoma cells through targeting the miR-381-3p/GFRA1 axis

Osteosarcoma is a common primary malignant bone cancer. Long noncoding RNA small nucleolar RNA host gene 15 (SNHG15) has been reported to play an oncogenic role in many cancers. Nevertheless, the role of SNHG15 in the doxorubicin (DXR) resistance of osteosarcoma cells has not been fully addressed.

Bibliographic Details
Main Authors: Zhang Jinshan, Rao Dan, Ma Haibo, Kong Defeng, Xu Xiaoming, Lu Hougen
Format: Article
Language:English
Published: De Gruyter 2020-12-01
Series:Open Life Sciences
Subjects:
osteosarcoma
snhg15
mir-381-3p
gfra1
cell proliferation
autophagy
chemoresistance
Online Access:https://doi.org/10.1515/biol-2020-0086

Internet

https://doi.org/10.1515/biol-2020-0086

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