Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis

Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis

Prostate cancer is the most frequent malignancy in European men and the second worldwide. One of the major oncogenic events in this disease includes amplification of the transcription factor cMYC. Amplification of this oncogene in chromosome 8q24 occurs concomitantly with the copy number increase in...

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Main Authors: Parastoo Shahrouzi, Ianire Astobiza, Ana R. Cortazar, Verónica Torrano, Alice Macchia, Juana M. Flores, Chiara Niespolo, Isabel Mendizabal, Ruben Caloto, Amaia Ercilla, Laura Camacho, Leire Arreal, Maider Bizkarguenaga, Maria L. Martinez-Chantar, Xose R. Bustelo, Edurne Berra, Endre Kiss-Toth, Guillermo Velasco, Amaia Zabala-Letona, Arkaitz Carracedo
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
TRIB1
prostate cancer
cMYC
mouse models
Online Access:https://www.mdpi.com/2072-6694/12/9/2593

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https://www.mdpi.com/2072-6694/12/9/2593

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