Fine-mapping angiotensin-converting enzyme gene: separate QTLs identified for hypertension and for ACE activity.

Fine-mapping angiotensin-converting enzyme gene: separate QTLs identified for hypertension and for ACE activity.

Angiotensin-converting enzyme (ACE) has been implicated in multiple biological system, particularly cardiovascular diseases. However, findings associating ACE insertion/deletion polymorphism with hypertension or other related traits are inconsistent. Therefore, in a two-stage approach, we aimed to f...

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Bibliographic Details
Main Authors: Chia-Min Chung, Ruey-Yun Wang, Cathy S J Fann, Jaw-Wen Chen, Yuh-Shiun Jong, Yuh-Shan Jou, Hsin-Chou Yang, Chih-Sen Kang, Chien-Chung Chen, Huan-Cheng Chang, Wen-Harn Pan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3587614?pdf=render

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http://europepmc.org/articles/PMC3587614?pdf=render

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