Cardioprotective Regimen of Adaptation to Chronic Hypoxia Diversely Alters Myocardial Gene Expression in SHR and SHR-mtBN Conplastic Rat Strains

Cardioprotective Regimen of Adaptation to Chronic Hypoxia Diversely Alters Myocardial Gene Expression in SHR and SHR-mtBN Conplastic Rat Strains

Adaptation to continuous normobaric hypoxia (CNH) protects the heart against acute ischemia/reperfusion injury. Recently, we have demonstrated the infarct size-limiting effect of CNH also in hearts of spontaneously hypertensive rats (SHR) and in conplastic SHR-mtBN strain characterized by the select...

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Bibliographic Details
Main Authors: Iveta Nedvedova, David Kolar, Jan Neckar, Martin Kalous, Michal Pravenec, Jan Šilhavý, Vlasta Korenkova, Frantisek Kolar, Jitka M. Zurmanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Endocrinology
Subjects:
SHR
conplastic strain
SHR-mtBN
left ventricle
hypoxia
metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00809/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00809/full

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