Potential roles of CCR5(+) CCR6(+) dendritic cells induced by nasal ovalbumin plus Flt3 ligand expressing adenovirus for mucosal IgA responses.

Potential roles of CCR5(+) CCR6(+) dendritic cells induced by nasal ovalbumin plus Flt3 ligand expressing adenovirus for mucosal IgA responses.

We assessed the role of CCR5(+)/CCR6(+)/CD11b(+)/CD11c(+) dendritic cells (DCs) for induction of ovalbumin (OVA)-specific antibody (Ab) responses following mucosal immunization. Mice given nasal OVA plus an adenovirus expressing Flt3 ligand (Ad-FL) showed early expansion of CCR5(+)/CCR6(+)/CD11b(+)/...

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Bibliographic Details
Main Authors: Yoshiko Fukuyama, Daisuke Tokuhara, Shinichi Sekine, Kazuyoshi Aso, Kosuke Kataoka, Julia Davydova, Masato Yamamoto, Rebekah S Gilbert, Yuka Tokuhara, Keiko Fujihashi, Jun Kunisawa, Yoshikazu Yuki, Hiroshi Kiyono, Jerry R McGhee, Kohtaro Fujihashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3615010?pdf=render

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http://europepmc.org/articles/PMC3615010?pdf=render

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