Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.

Thousands of long intergenic non-coding RNAs (lincRNAs) are encoded by the mammalian genome. However, the function of most of these lincRNAs has not been identified in vivo. Here, we demonstrate a role for a novel lincRNA, linc-MYH, in adult fast-type myofiber specialization. Fast myosin heavy chain...

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Bibliographic Details
Main Authors: Iori Sakakibara, Marc Santolini, Arnaud Ferry, Vincent Hakim, Pascal Maire
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4031048?pdf=render