RNA-Sequencing Based microRNA Expression Signature of Colorectal Cancer: The Impact of Oncogenic Targets Regulated by <i>miR-490-3p</i>

RNA-Sequencing Based microRNA Expression Signature of Colorectal Cancer: The Impact of Oncogenic Targets Regulated by <i>miR-490-3p</i>

To elucidate novel aspects of the molecular pathogenesis of colorectal cancer (CRC), we have created a new microRNA (miRNA) expression signature based on RNA-sequencing. Analysis of the signature showed that 84 miRNAs were upregulated, and 70 were downregulated in CRC tissues. Interestingly, our sig...

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Bibliographic Details
Main Authors: Yuto Hozaka, Yoshiaki Kita, Ryutaro Yasudome, Takako Tanaka, Masumi Wada, Tetsuya Idichi, Kan Tanabe, Shunichi Asai, Shogo Moriya, Hiroko Toda, Shinichiro Mori, Hiroshi Kurahara, Takao Ohtsuka, Naohiko Seki
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
microRNA
colorectal cancer
RNA-sequencing
expression signature
tumor-suppressor
<i>miR-490-3p</i>
Online Access:https://www.mdpi.com/1422-0067/22/18/9876

Internet

https://www.mdpi.com/1422-0067/22/18/9876

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