Mechanistic insight into the effects of Aryl Hydrocarbon Receptor activation on osteogenic differentiation

Mechanistic insight into the effects of Aryl Hydrocarbon Receptor activation on osteogenic differentiation

While inhibition of bone healing and increased rates of pseudarthrosis are known adverse outcomes associated with cigarette smoking, the underlying mechanisms by which this occurs are not well understood. Recent work has implicated the Aryl Hydrocarbon Receptor (Ahr) as one mediator of the anti-oste...

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Bibliographic Details
Main Authors: Chawon Yun, Joseph A. Weiner, Danielle S. Chun, Jonghwa Yun, Ralph W. Cook, Michael S. Schallmo, Abhishek S. Kannan, Sean M. Mitchell, Ryan D. Freshman, Christian Park, Wellington K. Hsu, Erin L. Hsu
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Bone Reports
Subjects:
Dioxin
TCDD
Aryl Hydrocarbon Receptor
Cigarette smoke
Bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187217300050

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http://www.sciencedirect.com/science/article/pii/S2352187217300050

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