Immune Resolution Dilemma: Host Antimicrobial Factor S100A8/A9 Modulates Inflammatory Collateral Tissue Damage During Disseminated Fungal Peritonitis

Immune Resolution Dilemma: Host Antimicrobial Factor S100A8/A9 Modulates Inflammatory Collateral Tissue Damage During Disseminated Fungal Peritonitis

Intra-abdominal infection (peritonitis) is a leading cause of severe disease in surgical intensive care units, as over 70% of patients diagnosed with peritonitis develop septic shock. A critical role of the immune system is to return to homeostasis after combating infection. S100A8/A9 (calprotectin)...

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Bibliographic Details
Main Authors: Madhu Shankar, Nathalie Uwamahoro, Emelie Backman, Sandra Holmberg, Maria Joanna Niemiec, Johannes Roth, Thomas Vogl, Constantin F. Urban
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
sepsis
host-pathogen interactions
peritonitis
Candida albicans
inflammation
S100A8/A9 complex
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.553911/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.553911/full

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