Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA regulators

Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA regulators

Summary: Small RNAs (sRNAs) are important gene regulators in bacteria. Many sRNAs act post-transcriptionally by affecting translation and degradation of the target mRNAs upon base-pairing interactions. Here we present a general approach combining imaging and mathematical modeling to determine kineti...

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Bibliographic Details
Main Authors: Matthew A. Reyer, Shriram Chennakesavalu, Emily M. Heideman, Xiangqian Ma, Magda Bujnowska, Lu Hong, Aaron R. Dinner, Carin K. Vanderpool, Jingyi Fei
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
bacterial small RNA
gene regulation
fluorescence microscopy
mathematical modeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721012183

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http://www.sciencedirect.com/science/article/pii/S2211124721012183

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