IMMUNOGLOBULIN GENE REPERTOIRE IN CHRONIC LYMPHOCYTIC LEUKEMIA: INSIGHT INTO ANTIGEN SELECTION AND MICROENVIRONMENTAL INTERACTIONS

Immunogenetic analysis of the B cell receptors (BcRs) has been a richly rewarding field for unraveling the pathogenesis of human lymphomas, including CLL. A biased immunoglobulin gene repertoire is seen as evidence for selection of CLL progenitor cells by antigen. Additional corroborative evidence i...

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Bibliographic Details
Main Authors: Efterpi Kostareli, Maria Gounari, Andreas Agathangelidis, Kostas Stamatopoulos
Format: Article
Language:English
Published: PAGEPress Publications 2012-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/352