Inhibitory Action of Antidiabetic Drugs on the Free Radical Production by the Rod Outer Segment Ectopic Aerobic Metabolism

Inhibitory Action of Antidiabetic Drugs on the Free Radical Production by the Rod Outer Segment Ectopic Aerobic Metabolism

Rod outer segments (OS) express the F<sub>o</sub>F<sub>1</sub>-ATP synthase and the respiratory chain, conducting an ectopic aerobic metabolism that produces free radicals in vitro. Diabetic retinopathy, a leading cause of vision loss, is associated with oxidative stress in t...

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Bibliographic Details
Main Authors: Silvia Ravera, Federico Caicci, Paolo Degan, Davide Maggi, Lucia Manni, Alessandra Puddu, Massimo Nicolò, Carlo E. Traverso, Isabella Panfoli
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
F<sub>o</sub>F<sub>1</sub>-ATP synthase
glybenclamide
diabetic retinopathy
light
metformin
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/9/11/1133

Internet

https://www.mdpi.com/2076-3921/9/11/1133

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