In vitro Selection of Chemically Modified DNAzymes

Abstract DNAzymes are in vitro selected DNA oligonucleotides with catalytic activities. RNA cleavage is one of the most extensively studied DNAzyme reactions. To expand the chemical functionality of DNA, various chemical modifications have been made during and after selection. In this review, we sum...

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Bibliographic Details
Main Authors: Prof. Po‐Jung Jimmy Huang, Prof. Juewen Liu
Format: Article
Language:English
Published: Wiley-VCH 2020-10-01
Series:ChemistryOpen
Subjects:
Online Access:https://doi.org/10.1002/open.202000134