Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in <i>Saccharomyces cerevisiae</i>

Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in <i>Saccharomyces cerevisiae</i>

Polygodial is a “hot” peppery-tasting sesquiterpenoid that was first described for its anti-feedant activity against African armyworms. Using the haploid deletion mutant library of <i>Saccharomyces cerevisiae</i>, a genome-wide mutant screen was performed to shed more light on polygodial...

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Bibliographic Details
Main Authors: Purity N. Kipanga, Liesbeth Demuyser, Johannes Vrijdag, Elja Eskes, Petra D’hooge, Josphat Matasyoh, Geert Callewaert, Joris Winderickx, Patrick Van Dijck, Walter Luyten
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
Polygodial
antifungal
<i>Saccharomyces cerevisiae</i>
haploid deletion mutant library
V-ATPase
vacuolar pH
Online Access:https://www.mdpi.com/1422-0067/22/11/5756

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