Yeast Stress, Aging, and Death

by Cristina Mazzoni, Sergio Giannattasio, Joris Winderickx, Paula Ludovico
Published 2013-01-01

Yeasts as Complementary Model Systems for the Study of the Pathological Repercussions of Enhanced Synphilin-1 Glycation and Oxidation

by David Seynnaeve, Daniel P. Mulvihill, Joris Winderickx, Vanessa Franssens
Published 2021-02-01

pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity

by Marie-Anne Deprez, Elja Eskes, Tobias Wilms, Paula Ludovico, Joris Winderickx
Published 2018-01-01

The Role of Sch9 and the V-ATPase in the Adaptation Response to Acetic Acid and the Consequences for Growth and Chronological Lifespan

by Marie-Anne Deprez, Jeroen M. Maertens, Lisbeth Olsson, Maurizio Bettiga, Joris Winderickx
Published 2021-09-01

A Mitochondria-Associated Oxidative Stress Perspective on Huntington’s Disease

by Ju Zheng, Ju Zheng, Ju Zheng, Joris Winderickx, Vanessa Franssens, Beidong Liu, Beidong Liu, Beidong Liu
Published 2018-09-01

Yeast as a Model System to Study Tau Biology

by Ann De Vos, Jayamani Anandhakumar, Jeff Van den Brande, Mathias Verduyckt, Vanessa Franssens, Joris Winderickx, Erwin Swinnen
Published 2011-01-01

The Impact of ESCRT on Aβ1-42 Induced Membrane Lesions in a Yeast Model for Alzheimer’s Disease

by Gernot Fruhmann, Christelle Marchal, Hélène Vignaud, Mathias Verduyckt, Nicolas Talarek, Claudio De Virgilio, Joris Winderickx, Christophe Cullin
Published 2018-11-01

Sphingolipids and Inositol Phosphates Regulate the Tau Protein Phosphorylation Status in Humanized Yeast

by Francisca Randez-Gil, Lino Bojunga, Francisco Estruch, Joris Winderickx, Maurizio Del Poeta, Maurizio Del Poeta, Jose A. Prieto
Published 2020-11-01

The peptidyl prolyl cis/trans isomerase Pin1/Ess1 inhibits phosphorylation and toxicity of tau in a yeast model for Alzheimer’s disease

by Ann De Vos, Tine Bynens, Joëlle Rosseels, Catherina Coun, Julia Ring, Frank Madeo, Marie-Christine Galas, Joris Winderickx, Vanessa Franssens
Published 2015-04-01

Recent Insights on Alzheimer’s Disease Originating from Yeast Models

by David Seynnaeve, Mara Del Vecchio, Gernot Fruhmann, Joke Verelst, Melody Cools, Jimmy Beckers, Daniel P. Mulvihill, Joris Winderickx, Vanessa Franssens
Published 2018-07-01

Neuroserpin Inclusion Bodies in a FENIB Yeast Model

by Valentina Vapore, Corrado Mazzaglia, Diego Sibilia, Mara Del Vecchio, Gernot Fruhmann, Marta Valenti, Elena Miranda, Teresa Rinaldi, Joris Winderickx, Cristina Mazzoni
Published 2021-07-01

Decreased Vacuolar Ca2+ Storage and Disrupted Vesicle Trafficking Underlie Alpha-Synuclein-Induced Ca2+ Dysregulation in S. cerevisiae

by Geert Callewaert, Petra D’hooge, Tien-Yang Ma, Tien-Yang Ma, Mara Del Vecchio, Vincent Van Eyck, Vanessa Franssens, Joris Winderickx
Published 2020-05-01

New perspectives from South-Y-East, not all about death. A report of the 12th lnternational Meeting on Yeast Apoptosis in Bari, Italy, May 14th-18th, 2017

by Nicoletta Guaragnella, Mariarita Stirpe, William Burhans, Manuela Côrte-Real, Campbell Gourlay, Paula Ludovico, Frank Madeo, Dina Petranovic, Joris Winderickx, Cristina Mazzoni, Sergio Giannattasio
Published 2018-01-01

Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in <i>Saccharomyces cerevisiae</i>

by Purity N. Kipanga, Liesbeth Demuyser, Johannes Vrijdag, Elja Eskes, Petra D’hooge, Josphat Matasyoh, Geert Callewaert, Joris Winderickx, Patrick Van Dijck, Walter Luyten
Published 2021-05-01

Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner.

by Sabrina Büttner, Charlotte Delay, Vanessa Franssens, Tine Bammens, Doris Ruli, Sandra Zaunschirm, Rita Machado de Oliveira, Tiago Fleming Outeiro, Frank Madeo, Luc Buée, Marie-Christine Galas, Joris Winderickx
Published 2010-10-01

The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability.

by Tobias Wilms, Erwin Swinnen, Elja Eskes, Laura Dolz-Edo, Alice Uwineza, Ruben Van Essche, Joëlle Rosseels, Piotr Zabrocki, Elisabetta Cameroni, Vanessa Franssens, Claudio De Virgilio, Gertien J Smits, Joris Winderickx
Published 2017-06-01

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

by Yann Fichou, Youssra K. Al-Hilaly, François Devred, Caroline Smet-Nocca, Philipp O. Tsvetkov, Joke Verelst, Joris Winderickx, Nick Geukens, Eugeen Vanmechelen, Audrey Perrotin, Louise Serpell, Bernard J Hanseeuw, Miguel Medina, Luc Buée, Isabelle Landrieu
Published 2019-03-01

Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer’s disease

by Michael Dumbacher, Tom Van Dooren, Katrien Princen, Koen De Witte, Mélissa Farinelli, Sam Lievens, Jan Tavernier, Wim Dehaen, Stefaan Wera, Joris Winderickx, Sara Allasia, Amuri Kilonda, Stéphane Spieser, Arnaud Marchand, Patrick Chaltin, Casper C. Hoogenraad, Gerard Griffioen
Published 2018-09-01

A Novel Tau Antibody Detecting the First Amino-Terminal Insert Reveals Conformational Differences Among Tau Isoforms

by Joke Verelst, Nick Geukens, Sabiha Eddarkaoui, Dorien Vliegen, Elien De Smidt, Joëlle Rosseels, Vanessa Franssens, Sofie Molenberghs, Cindy Francois, Erik Stoops, Maria Bjerke, Maria Bjerke, Sebastiaan Engelborghs, Sebastiaan Engelborghs, Mohamed Laghmouchi, Sofie Carmans, Luc Buée, Eugeen Vanmechelen, Joris Winderickx, Debby Thomas
Published 2020-03-01

Guidelines and recommendations on yeast cell death nomenclature

by Didac Carmona-Gutierrez, Maria Anna Bauer, Andreas Zimmermann, Andrés Aguilera, Nicanor Austriaco, Kathryn Ayscough, Rena Balzan, Shoshana Bar-Nun, Antonio Barrientos, Peter Belenky, Marc Blondel, Ralf J. Braun, Michael Breitenbach, William C. Burhans, Sabrina Büttner, Duccio Cavalieri, Michael Chang, Katrina F. Cooper, Manuela Côrte-Real, Vítor Costa, Christophe Cullin, Ian Dawes, Jörn Dengjel, Martin B. Dickman, Tobias Eisenberg, Birthe Fahrenkrog, Nicolas Fasel, Kai-Uwe Fröhlich, Ali Gargouri, Sergio Giannattasio, Paola Goffrini, Campbell W. Gourlay, Chris M. Grant, Michael T. Greenwood, Nicoletta Guaragnella, Thomas Heger, Jürgen Heinisch, Eva Herker, Johannes M. Herrmann, Sebastian Hofer, Antonio Jiménez-Ruiz, Helmut Jungwirth, Katharina Kainz, Dimitrios P. Kontoyiannis, Paula Ludovico, Stéphen Manon, Enzo Martegani, Cristina Mazzoni, Lynn A. Megeney, Chris Meisinger, Jens Nielsen, Thomas Nyström, Heinz D. Osiewacz, Tiago F. Outeiro, Hay-Oak Park, Tobias Pendl, Dina Petranovic, Stephane Picot, Peter Polčic, Peter Polčic, Mark Ramsdale, Mark Rinnerthaler, Patrick Rockenfeller, Christoph Ruckenstuhl, Raffael Schaffrath, Maria Segovia, Fedor F. Severin, Amir Sharon, Stephan J. Sigrist, Cornelia Sommer-Ruck, Maria João Sousa, Johan M. Thevelein, Karin Thevissen, Vladimir Titorenko, Michel B. Toledano, Mick Tuite, F.-Nora Vögtle, Benedikt Westermann, Joris Winderickx, Silke Wissing, Stefan Wölfl, Zhaojie J. Zhang, Richard Y. Zhao, Bing Zhou, Lorenzo Galluzzi, Guido Kroemer, Frank Madeo
Published 2018-01-01