Role of Pseudouridine Formation by Deg1 for Functionality of Two Glutamine Isoacceptor tRNAs

by Roland Klassen, Raffael Schaffrath
Published 2017-01-01

Unfolded Protein Response Suppression in Yeast by Loss of tRNA Modifications

by Alexander Bruch, Roland Klassen, Raffael Schaffrath
Published 2018-10-01

Decoding the biosynthesis and function of diphthamide, an enigmatic modification of translation elongation factor 2 (EF2)

by Raffael Schaffrath, Michael J. R. Stark
Published 2014-05-01

Role of <i>SSD1</i> in Phenotypic Variation of <i>Saccharomyces cerevisiae</i> Strains Lacking <i>DEG1</i>-Dependent Pseudouridylation

by Bahar Khonsari, Roland Klassen, Raffael Schaffrath
Published 2021-08-01

Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signaling

by Viktor Scheidt, André Jüdes, Christian Bär, Roland Klassen, Raffael Schaffrath
Published 2014-11-01

Sulfur transfer and activation by ubiquitin-like modifier system Uba4•Urm1 link protein urmylation and tRNA thiolation in yeast

by André Jüdes, Alexander Bruch, Roland Klassen, Mark Helm, Raffael Schaffrath
Published 2016-10-01

Autoselection of cytoplasmic yeast virus like elements encoding toxin/antitoxin systems involves a nuclear barrier for immunity gene expression.

by Alene Kast, Raphael Voges, Michael Schroth, Raffael Schaffrath, Roland Klassen, Friedhelm Meinhardt
Published 2015-05-01

Loss of anticodon wobble uridine modifications affects tRNA(Lys) function and protein levels in Saccharomyces cerevisiae.

by Roland Klassen, Pia Grunewald, Kathrin L Thüring, Christian Eichler, Mark Helm, Raffael Schaffrath
Published 2015-01-01

Roles of Elongator Dependent tRNA Modification Pathways in Neurodegeneration and Cancer

by Harmen Hawer, Alexander Hammermeister, Keerthiraju Ethiraju Ravichandran, Sebastian Glatt, Raffael Schaffrath, Roland Klassen
Published 2018-12-01

A Novel Sit4 Phosphatase Complex Is Involved in the Response to Ceramide Stress in Yeast

by Alexandra Woodacre, Museer A. Lone, Daniel Jablonowski, Roger Schneiter, Flaviano Giorgini, Raffael Schaffrath
Published 2013-01-01

Insights into Diphthamide, Key Diphtheria Toxin Effector

by Raffael Schaffrath, Michael J. R. Stark, Shanow Uthman, Viktor Scheidt, Wael Abdel-Fattah
Published 2013-05-01

Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast.

by Harmen Hawer, Koray Ütkür, Meike Arend, Klaus Mayer, Lorenz Adrian, Ulrich Brinkmann, Raffael Schaffrath
Published 2018-01-01

Redox requirements for ubiquitin-like urmylation of Ahp1, a 2-Cys peroxiredoxin from yeast

by Cindy Brachmann, Lars Kaduhr, André Jüdes, Keerthiraju Ethiraju Ravichandran, James D. West, Sebastian Glatt, Raffael Schaffrath
Published 2020-02-01

Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification

by Bruno Leonardo Bozaquel-Morais, Leonie Vogt, Valentina D’Angelo, Raffael Schaffrath, Roland Klassen, Mónica Montero-Lomelí
Published 2018-07-01

The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network.

by Shanow Uthman, Christian Bär, Viktor Scheidt, Shihui Liu, Sara ten Have, Flaviano Giorgini, Michael J R Stark, Raffael Schaffrath
Published 2013-01-01

Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.

by Wael Abdel-Fattah, Daniel Jablonowski, Rachael Di Santo, Kathrin L Thüring, Viktor Scheidt, Alexander Hammermeister, Sara Ten Have, Mark Helm, Raffael Schaffrath, Michael J R Stark
Published 2015-01-01

Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast

by Leticia Pollo-Oliveira, Roland Klassen, Nick Davis, Akif Ciftci, Jo Marie Bacusmo, Maria Martinelli, Michael S. DeMott, Thomas J. Begley, Peter C. Dedon, Raffael Schaffrath, Valérie de Crécy-Lagard
Published 2020-02-01

Use of a Yeast tRNase Killer Toxin to Diagnose Kti12 Motifs Required for tRNA Modification by Elongator

by Constance Mehlgarten, Heike Prochaska, Alexander Hammermeister, Wael Abdel-Fattah, Melanie Wagner, Rościsław Krutyhołowa, Sang Eun Jun, Gyung-Tae Kim, Sebastian Glatt, Karin D. Breunig, Michael J. R. Stark, Raffael Schaffrath
Published 2017-09-01

Guidelines and recommendations on yeast cell death nomenclature

by Didac Carmona-Gutierrez, Maria Anna Bauer, Andreas Zimmermann, Andrés Aguilera, Nicanor Austriaco, Kathryn Ayscough, Rena Balzan, Shoshana Bar-Nun, Antonio Barrientos, Peter Belenky, Marc Blondel, Ralf J. Braun, Michael Breitenbach, William C. Burhans, Sabrina Büttner, Duccio Cavalieri, Michael Chang, Katrina F. Cooper, Manuela Côrte-Real, Vítor Costa, Christophe Cullin, Ian Dawes, Jörn Dengjel, Martin B. Dickman, Tobias Eisenberg, Birthe Fahrenkrog, Nicolas Fasel, Kai-Uwe Fröhlich, Ali Gargouri, Sergio Giannattasio, Paola Goffrini, Campbell W. Gourlay, Chris M. Grant, Michael T. Greenwood, Nicoletta Guaragnella, Thomas Heger, Jürgen Heinisch, Eva Herker, Johannes M. Herrmann, Sebastian Hofer, Antonio Jiménez-Ruiz, Helmut Jungwirth, Katharina Kainz, Dimitrios P. Kontoyiannis, Paula Ludovico, Stéphen Manon, Enzo Martegani, Cristina Mazzoni, Lynn A. Megeney, Chris Meisinger, Jens Nielsen, Thomas Nyström, Heinz D. Osiewacz, Tiago F. Outeiro, Hay-Oak Park, Tobias Pendl, Dina Petranovic, Stephane Picot, Peter Polčic, Peter Polčic, Mark Ramsdale, Mark Rinnerthaler, Patrick Rockenfeller, Christoph Ruckenstuhl, Raffael Schaffrath, Maria Segovia, Fedor F. Severin, Amir Sharon, Stephan J. Sigrist, Cornelia Sommer-Ruck, Maria João Sousa, Johan M. Thevelein, Karin Thevissen, Vladimir Titorenko, Michel B. Toledano, Mick Tuite, F.-Nora Vögtle, Benedikt Westermann, Joris Winderickx, Silke Wissing, Stefan Wölfl, Zhaojie J. Zhang, Richard Y. Zhao, Bing Zhou, Lorenzo Galluzzi, Guido Kroemer, Frank Madeo
Published 2018-01-01