Decoding the biosynthesis and function of diphthamide, an enigmatic modification of translation elongation factor 2 (EF2)

by Raffael Schaffrath, Michael J. R. Stark
Published 2014-05-01

Insights into Diphthamide, Key Diphtheria Toxin Effector

by Raffael Schaffrath, Michael J. R. Stark, Shanow Uthman, Viktor Scheidt, Wael Abdel-Fattah
Published 2013-05-01

A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis

by Vasso Makrantoni, Adam Ciesiolka, Conor Lawless, Josefin Fernius, Adele Marston, David Lydall, Michael J. R. Stark
Published 2017-09-01

Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.

by Vasso Makrantoni, Stephen J Corbishley, Najma Rachidi, Nicholas A Morrice, David A Robinson, Michael J R Stark
Published 2014-01-01

The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network.

by Shanow Uthman, Christian Bär, Viktor Scheidt, Shihui Liu, Sara ten Have, Flaviano Giorgini, Michael J R Stark, Raffael Schaffrath
Published 2013-01-01

Phosphorylation of Elp1 by Hrr25 is required for elongator-dependent tRNA modification in yeast.

by Wael Abdel-Fattah, Daniel Jablonowski, Rachael Di Santo, Kathrin L Thüring, Viktor Scheidt, Alexander Hammermeister, Sara Ten Have, Mark Helm, Raffael Schaffrath, Michael J R Stark
Published 2015-01-01

Use of a Yeast tRNase Killer Toxin to Diagnose Kti12 Motifs Required for tRNA Modification by Elongator

by Constance Mehlgarten, Heike Prochaska, Alexander Hammermeister, Wael Abdel-Fattah, Melanie Wagner, Rościsław Krutyhołowa, Sang Eun Jun, Gyung-Tae Kim, Sebastian Glatt, Karin D. Breunig, Michael J. R. Stark, Raffael Schaffrath
Published 2017-09-01