The Architecture of the Rag GTPase Signaling Network

by Raffaele Nicastro, Alessandro Sardu, Nicolas Panchaud, Claudio De Virgilio
Published 2017-06-01

Amino Acids Stimulate TORC1 through Lst4-Lst7, a GTPase-Activating Protein Complex for the Rag Family GTPase Gtr2

by Marie-Pierre Péli-Gulli, Alessandro Sardu, Nicolas Panchaud, Serena Raucci, Claudio De Virgilio
Published 2015-10-01

Feedback Inhibition of the Rag GTPase GAP Complex Lst4-Lst7 Safeguards TORC1 from Hyperactivation by Amino Acid Signals

by Marie-Pierre Péli-Gulli, Serena Raucci, Zehan Hu, Jörn Dengjel, Claudio De Virgilio
Published 2017-07-01

Yeast Endosulfines Control Entry into Quiescence and Chronological Life Span by Inhibiting Protein Phosphatase 2A

by Séverine Bontron, Malika Jaquenoud, Stefania Vaga, Nicolas Talarek, Bernd Bodenmiller, Ruedi Aebersold, Claudio De Virgilio
Published 2013-01-01

TORC1 regulates Pah1 phosphatidate phosphatase activity via the Nem1/Spo7 protein phosphatase complex.

by Emmanuelle Dubots, Stéphanie Cottier, Marie-Pierre Péli-Gulli, Malika Jaquenoud, Séverine Bontron, Roger Schneiter, Claudio De Virgilio
Published 2014-01-01

The Impact of ESCRT on Aβ1-42 Induced Membrane Lesions in a Yeast Model for Alzheimer’s Disease

by Gernot Fruhmann, Christelle Marchal, Hélène Vignaud, Mathias Verduyckt, Nicolas Talarek, Claudio De Virgilio, Joris Winderickx, Christophe Cullin
Published 2018-11-01

Functional mapping of yeast genomes by saturated transposition

by Agnès H Michel, Riko Hatakeyama, Philipp Kimmig, Meret Arter, Matthias Peter, Joao Matos, Claudio De Virgilio, Benoît Kornmann
Published 2017-05-01

Multilayered Control of Protein Turnover by TORC1 and Atg1

by Zehan Hu, Serena Raucci, Malika Jaquenoud, Riko Hatakeyama, Michael Stumpe, Rudolf Rohr, Fulvio Reggiori, Claudio De Virgilio, Jörn Dengjel
Published 2019-09-01

Indole-3-acetic acid is a physiological inhibitor of TORC1 in yeast.

by Raffaele Nicastro, Serena Raucci, Agnès H Michel, Michael Stumpe, Guillermo Miguel Garcia Osuna, Malika Jaquenoud, Benoît Kornmann, Claudio De Virgilio
Published 2021-03-01

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock

by Andrea Brenna, Iwona Olejniczak, Rohit Chavan, Jürgen A Ripperger, Sonja Langmesser, Elisabetta Cameroni, Zehan Hu, Claudio De Virgilio, Jörn Dengjel, Urs Albrecht
Published 2019-11-01

The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability.

by Tobias Wilms, Erwin Swinnen, Elja Eskes, Laura Dolz-Edo, Alice Uwineza, Ruben Van Essche, Joëlle Rosseels, Piotr Zabrocki, Elisabetta Cameroni, Vanessa Franssens, Claudio De Virgilio, Gertien J Smits, Joris Winderickx
Published 2017-06-01