Development and validation of stability-indicating RP-HPLC method for the simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form

Development and validation of stability-indicating RP-HPLC method for the simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form

Abstract Background A simple, robust, precise, and an accurate HPLC method was established for simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from a nasal spray dosage form. The effective separation was obtained by injecting 10 μl of sample and standard solutions on...

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Bibliographic Details
Main Authors: Bhaskar Musmade, Prashant Sanatan, Surbhi Lokhande, Shrikant Kulkarni, Shrinivas Bhope, Sriram Padmanabhan, Amol Pachpinde, Kishan Lohar
Format: Article
Language:English
Published: SpringerOpen 2021-05-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
RP-HPLC
Method validation
Nasal spray
Ipratropium bromide
Xylometazoline
Stability study
Online Access:https://doi.org/10.1186/s43094-021-00247-x

Internet

https://doi.org/10.1186/s43094-021-00247-x

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