Acute toxicity evaluation of a novel ceramide analog for the treatment of breast cancer

Acute toxicity evaluation of a novel ceramide analog for the treatment of breast cancer

We have previously reported that treating triple-negative tumor bearing nude mice with intraperitoneal (ip) 10 mg/kg body weight of (S,E)-3-hydroxy-2-(2-hydroxybenzylidene)amino-N-tetradecylpropanamide, a ceramide analog, 5 days per week for 3 weeks, was shown not only to suppress tumor growth but a...

Full description

Bibliographic Details
Main Authors: Tulasi Ponnapakkam, Kyla Bongay-Williams, Teresa Beamon, Royce Hooks, Degrick Cheatham, Navneet Goyal, Muralidharan Anbalagan, Maryam Foroozesh
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Ceramide
Toxicology
Drug
Breast cancer
Biochemical parameters
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021001499

Internet

http://www.sciencedirect.com/science/article/pii/S2214750021001499

Similar Items