Activated mitochondrial dynamin-related protein 1 couples with LRRK2 to cause mitochondrial dysfunction in hypoxic cells

Activated mitochondrial dynamin-related protein 1 couples with LRRK2 to cause mitochondrial dysfunction in hypoxic cells

Objective To explore the mechanism of activated mitochondrial dynamin-related protein 1 (Drp1) in regulating mitochondrial energy metabolism and aerobic respiration after hypoxia. Methods We observed the changes of Drp1 activity and its relationship with mitochondrial damage by coimmunoprecipitation...

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Bibliographic Details
Main Authors: DUAN Chenyang, XIANG Xinming, KUANG Lei, LIU Liangming, LI Tao
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-02-01
Series:Di-san junyi daxue xuebao
Subjects:
hypoxia
dynamin-related protein 1
lrrk2
mitochondria
energy metabolism
aerobic respiration
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201910153.htm

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http://aammt.tmmu.edu.cn/Upload/rhtml/201910153.htm

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