Alterations in TP53, cyclin D2, c-Myc, p21WAF1/CIP1 and p27KIP1 expression associated with progression in B-CLL.
B-cell chronic lymphocytic leukaemia (B-CLL) originates from B lymphocytes that may differ in the activation level, maturation state or cellular subgroups in peripheral blood. Tumour progression in CLL B cells seems to result in gradual accumulation of the clone of resting B lymphocytes in the early...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Via Medica
2011-04-01
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Series: | Folia Histochemica et Cytobiologica |
Online Access: | http://czasopisma.viamedica.pl/fhc/article/view/4164 |