Alterations in TP53, cyclin D2, c-Myc, p21WAF1/CIP1 and p27KIP1 expression associated with progression in B-CLL.

B-cell chronic lymphocytic leukaemia (B-CLL) originates from B lymphocytes that may differ in the activation level, maturation state or cellular subgroups in peripheral blood. Tumour progression in CLL B cells seems to result in gradual accumulation of the clone of resting B lymphocytes in the early...

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Bibliographic Details
Main Authors: Marzec-Kotarska Barbara, Paterski Artur, Antosz Halina, Sajewicz Joanna, Dmoszyńska Anna
Format: Article
Language:English
Published: Via Medica 2011-04-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4164