Structural characteristic of the initial unfolded state on refolding determines catalytic efficiency of the folded protein in presence of osmolytes.

Structural characteristic of the initial unfolded state on refolding determines catalytic efficiency of the folded protein in presence of osmolytes.

Osmolytes are low molecular weight organic molecules accumulated by organisms to assist proper protein folding, and to provide protection to the structural integrity of proteins under denaturing stress conditions. It is known that osmolyte-induced protein folding is brought by unfavorable interactio...

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Bibliographic Details
Main Authors: Marina Warepam, Gurumayum Suraj Sharma, Tanveer Ali Dar, Md Khurshid Alam Khan, Laishram Rajendrakumar Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4196897?pdf=render

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http://europepmc.org/articles/PMC4196897?pdf=render

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