Identification of the Schistosoma mansoni TNF-alpha receptor gene and the effect of human TNF-alpha on the parasite gene expression profile.

BACKGROUND: Schistosoma mansoni is the major causative agent of schistosomiasis. The parasite takes advantage of host signals to complete its development in the human body. Tumor necrosis factor-alpha (TNF-alpha) is a human cytokine involved in skin inflammatory responses, and although its effect on...

Full description

Bibliographic Details
Main Authors: Katia C Oliveira, Mariana L P Carvalho, Thiago M Venancio, Patricia A Miyasato, Toshie Kawano, Ricardo DeMarco, Sergio Verjovski-Almeida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2779652?pdf=render