Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs
Nicotinic acetylcholine receptors (nAChRs) are targets for developing new drugs to treat severe pain, nicotine addiction, Alzheimer disease, epilepsy, etc. α-Conotoxins are biologically and chemically diverse. With 12–19 residues and two disulfides, they can be specifically selected for different nA...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-10-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-3397/14/10/173 |