Interactions among mTORC, AMPK and SIRT: a computational model for cell energy balance and metabolism

Abstract Background Cells adapt their metabolism and activities in response to signals from their surroundings, and this ability is essential for their survival in the face of perturbations. In tissues a deficit of these mechanisms is commonly associated with cellular aging and diseases, such as car...

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Bibliographic Details
Main Authors: Mehrshad Sadria, Anita T. Layton
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-021-00706-1