Guanylin, Uroguanylin and Guanylate Cyclase-C Are Expressed in the Gastrointestinal Tract of Horses

Guanylate cyclase-C (GC-C) is a multifunctional receptor encoded by the GUCY2C gene, representing an attractive target for therapy in several gastrointestinal diseases in humans. Little is known about this system in horses. We investigated for the first time the gene expression of guanylin, uroguany...

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Main Authors: Katia Cappelli, Rodolfo Gialletti, Beniamino Tesei, Gabrio Bassotti, Katia Fettucciari, Stefano Capomaccio, Laura Bonfili, Massimiliano Cuccioloni, Anna Maria Eleuteri, Andrea Spaterna, Fulvio Laus
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01237/full