Dietary chemoprevention of PhIP induced carcinogenesis in male Fischer 344 rats with tomato and broccoli.

The heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-B]pyridine (PhIP), found in meats cooked at high temperatures, has been implicated in epidemiological and rodent studies for causing breast, prostate, and colorectal cancers. A previous animal study using a xenograft model has shown that w...

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Bibliographic Details
Main Authors: Kirstie Canene-Adams, Karen S Sfanos, Chung-Tiang Liang, Srinivasan Yegnasubramanian, William G Nelson, Cory Brayton, Angelo M De Marzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842290?pdf=render