LMO2 at 25 years: a paradigm of chromosomal translocation proteins
LMO2 was first discovered through proximity to frequently occurring chromosomal translocations in T cell acute lymphoblastic leukaemia (T-ALL). Subsequent studies on its role in tumours and in normal settings have highlighted LMO2 as an archetypical chromosomal translocation oncogene, activated by a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2015-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150062 |