Systematic comparison of high-throughput single-cell RNA-seq methods for immune cell profiling

Systematic comparison of high-throughput single-cell RNA-seq methods for immune cell profiling

Abstract Background Elucidation of immune populations with single-cell RNA-seq has greatly benefited the field of immunology by deepening the characterization of immune heterogeneity and leading to the discovery of new subtypes. However, single-cell methods inherently suffer from limitations in the...

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Bibliographic Details
Main Authors: Tracy M. Yamawaki, Daniel R. Lu, Daniel C. Ellwanger, Dev Bhatt, Paolo Manzanillo, Vanessa Arias, Hong Zhou, Oh Kyu Yoon, Oliver Homann, Songli Wang, Chi-Ming Li
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Genomics
Subjects:
Single cell
Transcriptomics
Single-cell RNA-seq
High throughput sequencing
Immune-cell profiling
Online Access:https://doi.org/10.1186/s12864-020-07358-4

Internet

https://doi.org/10.1186/s12864-020-07358-4

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