Heterodimeric TALENs induce targeted heritable mutations in the crustacean Daphnia magna
Transcription activator-like effector nucleases (TALENs) are artificial nucleases harboring a customizable DNA-binding domain and a FokI nuclease domain. The high specificity of the DNA-binding domain and the ease of design have enabled researchers to use TALENs for targeted mutagenesis in various o...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2015-02-01
|
Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/4/3/364 |