Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria

Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria

Abstract Background Bovine TB (bTB), caused by infection with Mycobacterium bovis, is a major endemic disease affecting global cattle production. The key innate immune cell that first encounters the pathogen is the alveolar macrophage, previously shown to be substantially reprogrammed during intrace...

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Bibliographic Details
Main Authors: Thomas J. Hall, Michael P. Mullen, Gillian P. McHugo, Kate E. Killick, Siobhán C. Ring, Donagh P. Berry, Carolina N. Correia, John A. Browne, Stephen V. Gordon, David E. MacHugh
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Genomics
Subjects:
Alveolar macrophage
GWAS
Integrative genomics
Mycobacterium bovis
Network
RNA-seq
Online Access:https://doi.org/10.1186/s12864-021-07643-w

Internet

https://doi.org/10.1186/s12864-021-07643-w

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