Quantification of Circulating Cell Free Mitochondrial DNA in Extracellular Vesicles with PicoGreen™ in Liquid Biopsies: Fast Assessment of Disease/Trauma Severity

Quantification of Circulating Cell Free Mitochondrial DNA in Extracellular Vesicles with PicoGreen™ in Liquid Biopsies: Fast Assessment of Disease/Trauma Severity

The analysis of circulating cell free DNA (ccf-DNA) is an emerging diagnostic tool for the detection and monitoring of tissue injury, disease progression, and potential treatment effects. Currently, most of ccf-DNA in tissue and liquid biopsies is analysed with real-time quantitative PCR (qPCR) that...

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Bibliographic Details
Main Authors: Michela Marcatti, Jamal Saada, Ikenna Okereke, Charles E. Wade, Stefan H. Bossmann, Massoud Motamedi, Bartosz Szczesny
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
circulating cell free DNA
traumatic brain injury
trauma severity
extracellular veciscles
PicoGreen<sup>TM</sup> staining
Online Access:https://www.mdpi.com/2073-4409/10/4/819

Internet

https://www.mdpi.com/2073-4409/10/4/819

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