The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking

The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking

Viral interferon (IFN) antagonist proteins mediate evasion of IFN-mediated innate immunity and are often multifunctional, with distinct roles in viral replication. The Ebola virus IFN antagonist VP24 mediates nucleocapsid assembly, and inhibits IFN-activated signaling by preventing nuclear import of...

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Bibliographic Details
Main Authors: Angela R. Harrison, Cassandra T. David, Stephen M. Rawlinson, Gregory W. Moseley
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
Ebola virus
VP24
interferon antagonist
nuclear transport
nuclear export sequence
Online Access:https://www.mdpi.com/1999-4915/13/8/1650

Internet

https://www.mdpi.com/1999-4915/13/8/1650

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