Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945

Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945

Casein kinase 2 (CK2) regulates a plethora of proteins with pivotal roles in solid and hematological neoplasia. Particularly, in acute myeloid leukemia (AML) CK2 has been pointed as an attractive therapeutic target and prognostic marker. Here, we explored the impact of CK2 inhibition over the phosph...

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Bibliographic Details
Main Authors: Mauro Rosales, Arielis Rodríguez-Ulloa, Vladimir Besada, Ailyn C. Ramón, George V. Pérez, Yassel Ramos, Osmany Guirola, Luis J. González, Katharina Zettl, Jacek R. Wiśniewski, Yasser Perera, Silvio E. Perea
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
phosphoproteomics
casein kinase 2
kinase inhibitor
CX-4945
acute myeloid leukemia
Online Access:https://www.mdpi.com/2073-4409/10/2/338

Internet

https://www.mdpi.com/2073-4409/10/2/338

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